Friday, July 31, 2009

FATTY ACID ANALYSIS OF EMU OIL

Emu oil has recently received attention for its possible therapeutic and cosmetic benefits. The oil of the emu has been used for medicinal purposes by the Aborigines of Australia for many years and is currently being used in the cosmetic industry for its protective and softening effects of the skin. The exact mechanism by which emu oil exerts these effects is not known. Because several fatty acids are known to have potent physiological effect, it is important to characterize emu oil with respect to its fatty acid composition.

Fatty acids are classified according to chain length and by the number of double bonds, or points of unsaturation, in the chain. For example, palmitic acid is a fatty acid with sixteen carbons and no double bonds; thus in scientific nomenclature it is abbreviated as “16.0”. Because this fatty acid contains no double bonds, it is termed a “saturated” fatty acid. Fatty acids with one double bond (one point of unsaturation) are called “monounsaturated” fatty acids, and those with two or more double bonds are called “polyunsaturated” fatty acids. Oleic acid or 18:1 is a common monounsaturated fatty acid, and linoleic acid or 18:2 is a common polyunsaturated fatty acid. Any natural fat contains a mixture of all three types of fatty acids attached to a glycerol “backbone”. These compounds are called triglycerides. If a fat contains triglycerides made up of mostly saturated fatty acids, such as palmitic acid, then this fat is called a saturated fat.

The health effects of different types of fatty acids are well established. For example, saturated fat in the diet is known to raise blood cholesterol, but monounsaturated fats and polyunsaturated fats are known to lower blood cholesterol levels and thus reduce one’s risk for cardiovascular disease. Some polyunsaturated fatty acids are called “essential fatty acids” because they are necessary for the proper functioning of the body yet cannot be made by the body. Humans must get these fatty acids from dietary sources. Linoleic acid (18:2), an essential fatty acid for humans, is converted to arachidonic acid (20:4) which serves as a precursor for the powerful hormone-like compounds called “eicosanoids”. Eicosanoids serve normal functions in the body; however, they are produced in excessive amounts in some disease states such as arthritis. Concentrations of eicosanoids in the body can be manipulated by drugs (such as aspirin), by the type of fat in the diet, and in some cases, by fat administered in a topical manner.

Because there are no published scientific studies which have reported the fatty acid composition of emu oil, a study was undertaken at Auburn University to characterize the fatty acid composition of emu oil. The results from this investigation help to explain the properties and possible benefits of emu oil.

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